Navigating the NEST underground facility in Resident Evil 2 requires solving intricate terminal keypad puzzles to access vital areas and items. Players must enter specific symbol sequences into the Greenhouse Control Room terminal to unlock the ladder hatch and open the Drug Testing Lab fluid dispersal machine. Having a complete reference of these codes streamlines your progression through both first and second playthrough scenarios.

Greenhouse Control Room Terminal Overview

The main terminal in the Greenhouse Control Room serves as the access hub for the laboratory section. Instead of traditional numeric passcodes, this keypad utilizes blue symbol patterns mapped to grid positions. Entering the correct combinations grants access to the lower level via the hatch and allows players to synthesize the Herbicide.

First Run Lab Keypad Combinations

During the standard A Scenario, players can open the ladder hatch by inputting the sequence corresponding to positions 3, 1, 2, and 3 on the keypad grid. To unlock the Drug Testing Lab dispersal unit, the necessary combination follows the sequence 2, 10, 6, and 7. Inputting these codes early saves time and eliminates unnecessary backtracking through dangerous corridors filled with ivy mutated threats.

Second Run Keypad Code Variations

In the B Scenario or Second Run playthrough, Capcom changed the terminal combinations to present a new challenge to returning players. The Greenhouse ladder hatch code alters to the sequence 5, 8, 3, and 1. Meanwhile, the Drug Testing Lab unit requires the updated sequence 2, 10, 4, and 8 to unlock the synthesis system successfully.

In-Game Clue Locations and Solving Tips

If you prefer discovering solutions naturally, the ladder hatch code is visible directly on the metal hatch cover in the Greenhouse. The code for the Drug Testing Lab dispersal unit is hidden beneath a trophy found in the basement Lounge during the First Run. Examining the base of the trophy in your inventory reveals the engraved symbol pattern necessary for unlocking the machine.